- rare, idiopathic hypertrophic gastropathy
- patients usually present with epigastric pain and hypoalbuminemia (from loss of albumin into the gastric lumen)
- bimodal age distribution
- childhood form thought to be linked to cytomegalovirus infection
- diagnosis is made by combination of endoscopic and radiologic findings
- Upper GI series: thickened, lobulated folds in the gastric fundus which trap barium; hypersecretion may dilute barium which may prevent mucosal coating
- CECT: thickening of mucosa and submucosa which projects into the gastric lumen
- differential diagnosis
- Zollinger Ellison Syndrome - rugal fold thickening is not as pronounced, gastric ulcers, pancreatic involvement
- Gastritis - thickened folds usually in the antrum, H. pylori positive
- Lymphoma - thickened folds due to soft tissue masses not due to edema
REFERENCES
Friedman J, Platnick J, Farruggia S, et al. Menetrier Disease. Radiographics 2009;29:297-301.
Friedman J, Platnick J, Farruggia S, et al. Menetrier Disease. Radiographics 2009;29:297-301.
Kanne JP,
useful content,nice :)
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