Wednesday, November 7, 2012

Gastrointestinal Manifestations of Behcet Disease

Behcet disease (BD) is an idiopathic vasculitis affecting multiple organs. Involvement of the GI tract is seen in up to 50% of cases. Specific GI tract manifestations include:

  • ulceration: most common finding
    • localized - usually in the ileocecal region
    • diffuse - usually in the colon
    • ulcers are deep, often penetrating to the serosal layer 
    • recur at surgical anastamotic sites
  • thickened mucosal folds in the small bowel
  • increased incidence of fistulas and perforations
    • microperforations are common due to deep, penetrating nature of ulcers

Chae EJ, Do KH, Seo JB, et al. Radiologic and clinical findings of Behcet disease: comprehensive review of multisystemic involvement. Radiographics 2008;28:e31.
Chung SY, Ha HK, Kim JH, et al. Findings of Behcet syndrome involving the gastrointestinal tract. Radiographics 2001;21:911-24.

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