Wednesday, October 31, 2012
Splenic sequestration is seen in patients with sickle cell disease. It is due to trapping of red blood cells in the spleen's tortuous microcirculation. During sequestration the spleen is enlarged. On CECT studies (as above), peripheral low attenuation with high attenuation of the hilum is seen. MR imaging may demonstrate patchy areas of abnormal signal intensity on both T1 and T2 weighted images. On T1WI, a hyperintense region with peripheral low intensity will be seen in subacute hemorrhage.
Lonergan GJ, Cline DB, and Abbondanzo SL. Sickle cell anemia. Radiographics 2001;21:971-94.
Rabushka LS, Kawashima A, and Fishman EK. Imaging of the spleen: CT with supplemental MR examination. Radiographics 1994;14:307-32.