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Multiple
- Pleural metastases: Case shown above (Ewing sarcoma)
- Asbestos related pleural disease: Look for calcifications.
- Malignant mesothelioma: Diffuse nodular pleural thickening, thicker at lung bases, with a small hemithorax and pleural effusion. Grows along fissures.
- Invasive thymoma: Pleural metastases rare, but well-described.
- Lymphoma: Look for other enlarged nodes.
- Splenosis: Left-sided pleural thickening in a patient with history of distant trauma and an absent spleen.
Solitary
- Pleural metastases:
- Solitary fibrous tumor of the pleura: Hypervascular mobile mass displacing rather than invading adjacent structures. No chest wall involvement. Calcifications are more common in malignant lesions, but malignant and benign tumors are indistinguishable on imaging.
- Lipoma: Like solitary fibrous tumors of the pleura, pleural lipmas may also be pedunculated and mobile.
- Malignant mesothelioma:
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