Nasal Septal Perforation

Nasal septal perforation can be seen with the following conditions:

• Cocaine use: Most common cause of nasal septal perforation.
• Trauma: Ischemic necrosis due to compression from hematoma, iatrogenic.
• Wegener granulomatosis: Associated with soft tissue.
• Sarcoidosis: Associated with soft tissue.
• Non-Hodgkin Lymphoma: Associated with soft tissue.
• Infection: Invasive fungal sinusitis, Nasal septal abscess, Klebseilla (rhinoscleroma), syphilis (look for saddle nose deformity), tuberculosis, leprosy.
• Squamous cell carcinoma:
• Melanoma:

References

• STATdx.
• Case review series: Head and Neck (2nd ed.).