The image above is from a patient with Ewing sarcoma of the distal left femur. The primary lesion (black arrow) and bony metastases are clearly seen on the MIP image from the 18F-FDG PET study, while the bone scan only shows the uptake in the area of periosteal reaction (pink arrow) and a right anterior rib lesion that likewise was associated with cortical breakthrough and a periosteal reaction. MRI shows the primary lesion (black arrow), as well as metastases in the left and right femurs (blue arrows).
- Völker T, Denecke T, Steffen I, Misch D, Schönberger S, Plotkin M, Ruf J, Furth C, Stöver B, Hautzel H, Henze G, Amthauer H. Positron emission tomography for staging of pediatric sarcoma patients: results of a prospective multicenter trial. J Clin Oncol. 2007 Dec 1;25(34):5435-41.
- Walter F, Czernin J, Hall T, Allen-Auerbach M, Walter MA, Dunkelmann S, Federman N. Is there a need for dedicated bone imaging in addition to 18F-FDG PET/CT imaging in pediatric sarcoma patients? J Pediatr Hematol Oncol. 2012 Mar;34(2):131-6.