The Arnold-Hilgartner staging system that describes articular changes as the patient progresses through the stages of the disease.
- Stage I: Soft-tissue swelling from hemarthrosis or bleeding
into the periarticular soft tissues. No skeletal abnormality.
- Stage II: Osteoporosis and overgrowth of the epiphysis without bone cysts or narrowing of the cartilage space.
- Stage III: Early subchondral bone cysts, squaring of patella, widening of intercondylar notch of distal femur or humerus, preserved cartilage space. This is the final stage at which hemophilic arthropathy is reversible with treatment.
- Stage IV: Characterized by narrowing of cartilage space. More advanced findings of stage III are also seen.
- Stage V (shown above): Fibrous joint contracture (as seen in the attempted frontal view), loss of joint cartilage space, marked enlargement of epiphyses, and substantial disorganization of the joint.
References
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