Monday, April 19, 2010

MRI Findings in Hypoglycemic Encephalopathy

Kang et al describe the DWI findings in 11 cases of hypoglycemic encephalopathy. They found symmetric, potentially reversible diffusion restriction in the centrum semiovale (82%), cortex (73%), corona radiata (64%), internal capsule (54%), and hippocampus (36%). The cortical involvement was limited to the frontal and parietal lobes in a non-vascular distribution. Unlike prior reports, they did not find lesions in the corpus callosu. None of the lesions enhanced.

These findings are nonspecific and may be seen in a variety of ischemic and metabolic disorders. Specifically, reversible diffusion restriction can also be seen in seizure, drug toxicity, viral encephalitis, and metabolic encephalopathy.

References

Kang EG, Jeon SJ, Choi SS, Song CJ, Yu IK. Diffusion MR imaging of hypoglycemic encephalopathy. AJNR Am J Neuroradiol. 2010 Mar;31(3):559-64.

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