Gamna-Gandy Bodies

Gamna-Gandy bodies of the spleen are organized hemorrhagic foci caused by portal hypertension. They appear as low-signal lesions throughout the spleen on MRI. Here we see T2-weighted (top) and pre-contrast (middle) and portal venous phase gradient echo T1-weighted images showing multiple hypointense splenic lesions in a patient with cirrhosis and hepatocellular carcinoma. CT didn't show any focal splenic lesions.

References

Sagoh T, Itoh K, Togashi K, Shibata T, Nishimura K, Minami S, Asato R, Noma S, Fujisawa I, Yamashita K, et al. Gamna-Gandy bodies of the spleen: evaluation with MR imaging. Radiology. 1989 Sep;172(3):685-7.