Sunday, December 25, 2011


Dysgerminomas are the ovarian counterpart of testicular seminoma. Dysgerminomas are the second most common ovarian germ cell tumor and the most common malignant germ cell tumor. They are most commonly seen in girls and young women in the 2nd and 3rd decades of life.

The majority of tumors are pure dysgerminomas, which do not secrete any hormones. About 5%, however, contain syncytiotrophoblastic giant cells and produce β−hCG.

Dysgerminomas are multilobulated, usually unilateral, solid masses that can contain speckled calcifications (pink arrow), prominent fibrovascular septa, and central low-attenuation areas representing necrosis and hemorrhage (white arrow).

The differential diagnosis for ovarian neoplasms with calcification was covered earlier.


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