Saturday, January 2, 2010

Pulmonary-Renal Syndromes

Pulmonary-renal syndromes are clinical syndromes defined by a combination of diffuse alveolar haemorrhage (blood on serial bronchoalveolar lavage) and glomerulonephritis.
  • Primary systemic vasculitis (+ANCA): Wegener granulomatosis, microscopic polyangiitis, Churg–Strauss syndrome
  • Primary systemic vasculitis (-ANCA): Henoch–Schönlein purpura, mixed cryoglobulinaemia, Behçet disease, IgA nephropathy
  • Goodpasture syndrome: Autoantibodies to type IV collagen in alveolar and glomerular basement membrane.
  • Autoimmune: Systemic lupus erythematosus, scleroderma, polymyositis, rheumatoid arthritis, mixed collagen vascular disease
  • Drug-Related: Propylthiouracil, D-penicillamine, hydralazine, allopurinol, sulfasalazine
  • Thrombotic microangiopathy: Antiphospholipid syndrome, thrombotic thrombocytopenic purpura, infection, neoplasm


Papiris SA, Manali ED, Kalomenidis I, Kapotsis GE, Karakatsani A, Roussos C. Bench-to-bedside review: pulmonary-renal syndromes--an update for the intensivist. Crit Care. 2007;11(3):213.

No comments:

Post a Comment

Note: Only a member of this blog may post a comment.