The ITB may or may not be thickened in iliotibial band syndrome. Early on in the disease process, there may be fluid signal deep to the iliotibial band that may be difficult or impossible to differentiate from joint fluid that has extended posterolaterally. As the disease progresses, there is fluid surrounding the ITB, making the diagnosis easier.
T2 hyperintensity deep to the ITB is located within a space bounded superiorly by the vastus lateralis muscle, posteriorly by the biceps femoris muscle, laterally by the ITB, distally and medially by the meniscocapsular junction of the lateral meniscus, the lateral collateral ligament, and the lateral femoral epicondyle.
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