Clumped enhancement is a type of nonmasslike enhancement in which there is an aggregate of enhancing masses or foci that may be confluent in a cobblestone pattern. Clumped enhancement is suspicious for ductal carcinoma in situ (DCIS) and biopsy is generally recommended.
While the most commonly reported MR manifestation of DCIS is clumped nonmasslike enhancement in a ductal, linear, segmental, or regional distribution, other patterns have also been observed. These include a linear-ductal pattern of enhancement; segmental, focal, or regional area of enhancement; diffuse enhancement; and an enhancing mass.
High-grade DCIS more commonly manifests as an enhancing mass than do intermediate- or low-grade DCIS.
References
- Liberman L, Morris EA, Dershaw DD, Abramson AF, Tan LK. Ductal enhancement on MR imaging of the breast. AJR Am J Roentgenol. 2003 Aug;181(2):519-25.
- Mossa-Basha M, Fundaro GM, Shah BA, Ali S, Pantelic MV. Ductal carcinoma in situ of the breast: MR imaging findings with histopathologic correlation. Radiographics. 2010 Oct;30(6):1673-87.
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