Tuesday, April 3, 2012

Drugs and Cardiac FDG Uptake

Certain drugs and patient factors can affect cardiac uptake of FDG.

Drug Effect Comment
Similar to the effect of eating close to FDG administration. Will also cause diffuse increase in muscle uptake and a decrease in liver uptake.
Fibrate drug used for hyperlipidemia.


Shown above. Increases colonic FDG uptake and can result in a competitive decrease in cardiac FDG uptake.

In addition to the above, certain patient factors can increase cardiac FDG uptake: Male gender, younger patients (< 30 years), fasting duration of <5 hours, and patients with heart failure tend to have higher cardiac FDG uptake.


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