Monday, March 12, 2012

Diffusely Increased FDG Activity in the Thyroid

The thyroid may occasionally have diffusely increased uptake on FDG-PET scans obtained for malignancy elsewhere. Between 1%-3% of patients undergoing a PET scan will have such uptake. This finding can be seen as a normal variant or associated with chronic lymphocytic (Hashimoto) thyroiditis, with or without the presence of hypothyroidism and can be seen even in patients receiving thyroid hormone replacement therapy.

Focal uptake in the thyroid should raise concern for carcinoma or metastasis.


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