Monday, January 28, 2013

Causes of UPJ Obstruction

  • Abnormality of collagen muscle causing stenosis at the UPJ
  • High ureteral insertion
  • Aberrant crossing renal vessels: arteries/vein at the renal hilum crossing anterior or posterior to the ureter can cause obstruction
  • Failure of recanalization of the ureter (considered less likely)
  • Presence of valves/kinks (considered less likely)
  • Vesicoureteral reflux
  • Stricture or stenosis secondary to trauma, recurrent infection, instrumentation, calculi
  • Neoplasm: benign (polyp) or malignant (transitional cell, squamous cell)

Lawler LP, Jarret TW, Corl FM, Fishman EK. Adult ureteropelvic junction obstruction: insights with three-dimensional multi-detector row CT. Radiographics 2005;25:121-34.

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