The GraftJacket® matrix is an acellular human dermal matrix made by Wright Medical Technology that is processed to remove the epidermis and dermal cells, leaving an acellular scaffold of collagen, elastin, chondroitin sulfate, proteoglycans, hyaluronic acid, laminin, tenacin, and fibroblast growth factor. The acellular nature is thought to make it less immunogenic. The scaffold is supposed to provide strength as well as an intact extracellular framework with preserved vascular channels to support rapid revascularization and cellular repopulation. The system can be used to augment or replace irreparable portions of the rotator cuff tendon.
In the shoulder, the GraftJacket is used to span the cuff tear in younger, more active patients who have irreparable rotator cuff tears. Ideally, patients are motivated, intelligent, and younger and have disabling pain but an intact biceps tendon and well-maintained active motion with a functioning subscapularis muscle. The biceps tendon is used as an anterior anchor point for the graft.
References
- Barber FA, Burns JP, Deutsch A, Labbé MR, Litchfield RB. A Prospective, Randomized Evaluation of Acellular Human Dermal Matrix Augmentation for Arthroscopic Rotator Cuff Repair. Arthroscopy. 2011 Oct 5.
- Bond JL, Dopirak RM, Higgins J, Burns J, Snyder SJ. Arthroscopic replacement of massive, irreparable rotator cuff tears using a GraftJacket allograft: technique and preliminary results. Arthroscopy. 2008 Apr;24(4):403-409.e1.
- Wong I, Burns J, Snyder S. Arthroscopic GraftJacket repair of rotator cuff tears. J Shoulder Elbow Surg. 2010 Mar;19(2 Suppl):104-9.
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