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A shallow sella turcica can be a normal variant seen in about 15% of the population. It can also be associated with certain congenital anomalies and syndromes, such as Cockayne syndrome, Prader-Willi syndrome, basal cell nevus syndrome, Down syndrome, Hallerman-Streiff syndrome, and myotonic dystrophy. It can also be due to underdevelopment of the pituitary or decreased intracranial pressure.
References
- Castriota-Scanderbeg A and Dallapiccola B. Abnormal skeletal phenotypes: from simple signs to complex diagnoses (Springer, 2005), p 67.
- Keats TE and Anderson MW. Atlas of Normal Roentgen Variants That May Simulate Disease - 8th edition (Mosby, 2004), p 115.
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