Spotted Spleen

A spotted spleen, one with multiple low-attenuation nodules, is an uncommon finding that can be seen with:

• Tumor: Lymphoma (most common), metastases, hemangioma (most common benign splenic tumor).
• Infectious: Fungal, mycobacterial (tuberculosis shown above), or parasitic. More frequent in immunosuppressed patients.
• Inflammatory: Sarcoid is the most common

References

Warshauer DM, Molina PL, Worawattanakul S. The spotted spleen: CT and clinical correlation in a tertiary care center. Comput Assist Tomogr. 1998 Sep-Oct;22(5):694-702.