Differential Diagnosis of Orbital Globe Lesions

A brief differential diagnosis for globe lesions in adults:

• Blood: Low signal intensity on T1- and T2-weighted images when acute.
• Uveal melanoma: High signal on T1-weighted images. Low on T2-weighted images.
• Metastases: Bilateral in 30% of cases.
• Choroidal lymphoma:
• Congential vascular hamartoma: Also known as choroidal hemangioma. High signal on T1- and T2-weighted images.
• Retinal detachment: Y-shaped structure with its apex at the optic disk and its ends extending toward ciliary bodies.
• Choroidal detachment: High-attenuation, low signal intensity lines that are parallel to the choroidal plane and do not converge at the optic disk.