Positive Triple-Phase Bone Scan: Differential Diagnosis

Differential Diagnosis for Positive Triple-Phase Bone Scan The following conditions will result in increased activity in all three phases of a triple-phase bone scan (blood flow, blood pool, delayed) :

• Osteomyelitis
• Fracture
• Tumor
• Osteoid osteoma
• Charcot joint
• Reflex sympathetic dystrophy: Uptake involves entire extremity. 50% of patients have increased blood flow and blood pool uptake, while 95% have increased uptake on delayed images.
• Osteonecrosis
• Osteoarthritis