Differential considerations for epidural masses include:
- Degenerative: Disc herniation, facet osteophytosis, ligamentum flavum hypertrophy, synovial cyst, ossification of the posterior longitudinal ligament
- Epidural lipomatosis: Prominent epidural fat. Seen with prolonged steroid administration or Cushing syndrome. Y-shaped configuration of thecal sac on axial images is characteristic.
- Fluid collections: Pseudomeningocele, hematoma, abscess, arachnoid cyst.
- Metastasis: The lesion shown here ended up being Ewing sarcoma.
- Lymphoma
- Nerve sheath tumors: Nodular, fusiform, or dumbbell-shaped mass associated with nerve roots.
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