The CTA spot sign is a focus of enhancement within acute intracranial hematomas that is associated with expansion of an acute hematoma. Expansion of hematoma is, in turn, associated with increased mortality and diminished functional outcomes.
Other risk factors for hematoma expansion include hyperglycemia,hypertension, and anticoagulation.
References
Wada R, Aviv RI, Fox AJ, Sahlas DJ, Gladstone DJ, Tomlinson G, Symons SP. CT angiography "spot sign" predicts hematoma expansion in acute intracerebral hemorrhage. Stroke. 2007 Apr;38(4):1257-62.
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