Periosteal Reaction in Pediatrics

The differential diagnosis of periosteal reaction in pediatrics includes:

• Physiologic: Due to rapid growth
• Infection/inflammation
• Healing fracture
• Metabolic: Scurvy, vitamin A or D toxicity, Gaucher disease, etc.
• Tumor
• Prematurity: May be due to prostaglandin E, metabolic disease of prematurity, physiologic
• Melorheostosis

References

Musculoskeletal Radiology: The Requisites. Third edition. Chapter 3.