![](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEj7KaA1B84WwmVEDvBAm34G16y2BsLBDVc1n17xoSE51qTcKzfsmnfYElHotmUhxOzWF7P_COxdI2UejTXwjTmR_AxUMVJEd66ucfW7u5tio1dbkOM1qTt5EwUvOx5HgPT8CWV2hyIZnJPB/s400/superscan.jpg)
Differential considerations include:
- Metabolic disease: Renal osteodystrophy, osteomalacia, myelofibrosis. Often has a diffuse and homogeneous appearance on bone scan.
- Metastatic disease: Typically prostate, lung, and breast. May see some focal areas of increased uptake on bone scan.
More recently a super-superscan has been described, representing superimposed metastatic and metabolic superscan. This appearance may obscure recognition of osseous metastases.
References
- Liu Y. Super-superscan on a bone scintigraphy. Clin Nucl Med. 2011 Mar;36(3):227-8.
- Mettler FA and Guiberteau MJ. Chapter 9: Skeletal System. In Essentials of Nuclear Medicine Imaging. Fifth Edition. Saunders, Philadelphia. 2006
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