Patients receiving radiation therapy may develop photopenic areas on bone scan corresponding to the radiation therapy portal. Radiation-induced photopenia tends to occur at least 2 months following therapy. A dose of at least 20 Gy is apparently needed, and the effect saturates at about 50 Gy.
References
Hattner RS, Hartmeyer J, Wara WM. Characterization of radiation-induced photopenic abnormalities on bone scans. Radiology. 1982 Oct;145(1):161-3.
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